One of the most prominent memories of Imam Hussain is the sermon he delivered in the desert of Mina two years before Muawiya's death. In this sermon, Imam Hussain has pointed out the identity that science gives to scientists and the duties that scientists have towards the society in the best way and explained its relationship. This research, using a descriptive analytical method, aims to explain and present the relationship between "science, science and science" based on Imam Hossein's sermon in the desert of Mina. This research has used documentary method to collect information. In this research, the identity effect of science on scholars has been pointed out, and further, based on this identity, the role of scholars in a society has been examined and explained from the perspective of Imam Hossein. Among the findings of the research, besides the explanation of this relationship in Hosseini's words, is paying attention to the real position of science and the scientist and their historical mission, which attention can cause the right direction and Jihad movement in the current of existing science.